Metabolism of sodium oestrone [35S] sulphate in the rat
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منابع مشابه
Metabolism of sodium oestrone ( 35 S) sulphate in the guinea pig.
Intraperitoneal administration of sodium oestrone [(35)S]sulphate to male and female free-ranging guinea pigs is followed by excretion of most of the radioactivity mainly as inorganic [(35)S]sulphate in the urine within 72h. The remainder of the radioactivity in the urine was found in oestrone [(35)S]sulphate, two unidentified metabolites (A and B) and traces of oestradiol-17beta 3-[(35)S]sulph...
متن کاملThe Metabolism of L-serylglycine O(35s)-sulphate in the Rat.
1. The preparation of potassium l-serylglycine O-sulphate and the corresponding (35)S-labelled ester is described. 2. Intraperitoneal injection of potassium l-serylglycine O[(35)S]-sulphate to rats results in about 75% of the radioactivity of the dose appearing in the urine within 48hr. Almost 72% of the radioactivity recovered in the urine was in the form of inorganic [(35)S]sulphate. 3. Analy...
متن کاملThe effect of oestrone on the metabolism of rat uterus.
IT has been established that injection of oestrogenic hormone causes an increase in the rate of metabolism of certain tissues. Thi's has been shown for uterus by several workers (for literature see Tesauro [1936]), for ovary by Kiyohara & Izawa [1936], for anterior pituitary and for liver by Victor & Andersen [1937], Andersen & Victor [1938]; the latter workers, as well as Kiyohara & Izawa, sho...
متن کاملThe metabolic fate of chondroitin (35S)sulphate proteoglycan in the rat.
Revell & Muir (1972) have studied the metabolism of 35S-labelled proteoglycan from porcine cartilage after injection into guinea pigs. They concluded that the polymeric material excreted in the urine was the result of proteolytic degradation of the injected proteoglycan to single chains of chondroitin sulphate. These results are particularly interesting with respect to the site(s) and mechanism...
متن کاملGrowth of the cartilages of the mid-line cranial base of the Wistar rat: an autoradiographic study using 35S-sulphate.
Matrix synthesis in the mid-line cranial base of the rat was studied using a single injection of 35S-sulphate in animals aged 4-80 days. High uptake of 35S-sulphate in the morphologically distinct zone of early hypertrophy led to it being renamed the Matrixogenic Zone. Relocation of 35S-sulphate label into the primary spongiosa was used to estimate the growth rate of each site of endochondral o...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1970
ISSN: 0306-3283
DOI: 10.1042/bj1190022p